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(5) The dysfunctional alteration of membrane permeability causes restriction over ionic transport, which leads to Parkinson’s disease, Alzheimer’s disease, cystic fibrosis, and many other diseases. Nature has developed several ionophores for proper functioning of fundamental biological processes like muscle contraction, signal transduction, nerve impulse, hormonal regulation, apoptosis, etc. (4) These ionophores operate via transportation of inorganic and molecular ions across the semipermeable cellular membrane. ![]() The current decade evidences an increasing interest in artificial ionophores (1,2) because of their potential appliances in various technological (3) and biomedical fields.
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